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Author(s):
Yousif Ahmad
,
Gregory YH Lip
Added:
3 years ago
Atrial fibrillation (AF) leads to a prothrombotic state1 and places patients at risk of thromboembolic disease. The most common and serious complication of thromboembolism is stroke, and AF is held responsible for 25 % of all strokes.2 Strokes in the context of AF are associated with a higher mortality, longer hospital stay and lower levels of independence at discharge.3 These factors combine to…
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Atrial Myopathy Underlying AF
Author(s):
Harold Rivner
,
Raul D Mitrani
,
Jeffrey J Goldberger
Added:
3 years ago
Article
Author(s):
Rakesh Latchamsetty
,
Fred Morady
Added:
3 years ago
Catheter ablation of AF has shown steady growth over the past two decades with a nearly 15 % annual increase in the US.1 This growth can be attributed in large part to four factors: an increase in operators and institutions performing the procedure;2 a steady rise in AF prevalence, which is predicted to reach 12 million in the US by 2030;3 a larger spectrum of AF patients with more complex atrial…
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Author(s):
Tina Baykaner
,
Junaid Zaman
,
Paul J Wang
,
et al
Added:
3 years ago
Treatment of atrial fibrillation (AF) classically focuses on eliminating triggers near and from the pulmonary veins, which may initiate AF. However, the 1–2 year success rate of pulmonary vein isolation (PVI) remains 40–50% for persistent AF1,2 and 50–65% for paroxysmal AF,3–5 while supplementary linear lesions or extensive ablation at electrogram-targets have had disappointing results and may…
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Hybrid Ablation of Atrial Fibrillation
Author(s):
Laurent Pison
Start date:
Feb 26, 2015
Broadcast
Added:
6 years ago
Author(s):
Ling Zhang
,
Yuemei Hou
,
Sunny S Po
Added:
3 years ago
Atrial fibrillation(AF) is the most frequently encountered arrhythmia in clinical practice and has become an emerging epidemic. AF is associated with increased cardiovascular mortality and morbidy such as stroke.1–3 Over 2.3 million people in the US are affected by AF: it is estimated that AF will affect more than 15 million Americans by 2050.3 The traditional risk factors implicated in the…
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Author(s):
Demosthenes G Katritsis
,
Bernard J Gersh
,
A John Camm
Added:
3 years ago
Thrombotic material in atrial fibrillation(AF) usually develops in the left atrial appendage as a result of decreased flow and stasis, possible endothelial dysfunction and a hypercoagulable state as indicated by increased fibrinogen, D-dimer, thromboglobulin and platelet factor 4 levels.1 In the Framingham Heart Study, the percentage of strokes attributable to AF increases steeply from 1.5 % in…
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Author(s):
Jean-Baptiste Gourraud
,
Jason G Andrade
,
Laurent Macle
,
et al
Added:
3 years ago
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia observed in clinical practice, occurring in approximately 2 % of the general population.1–3 A progressive increase in both the prevalence and incidence of AF has been demonstrated in recent years, defining AF as a major economic and public health issue.1
The identification of sites of AF initiation and/or maintenance within…
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Author(s):
Dario DiFrancesco
Added:
3 years ago
HCN4 (hyperpolarisation-activated, cyclic nucleotide gated 4) channels, the pore-forming α–subunits of ‘funny’ channels originally described in pacemaker cells of the sinoatrial node (SAN),1 are responsible for the early phase of diastolic depolarisation in these cells and are key determinants of pacemaker generation and control of heart rate.2–5 HCN4 channels are selectively expressed in the SAN…
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