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Author(s):
George D Katritsis
,
Vishal Luther
,
Prapa Kanagaratnam
,
et al
Added:
3 years ago
The introduction of cardiac electroanatomic mapping systems in the mid-1990s has permitted investigators to record intracardiac electrograms (EGMs) with accurate spatial localisation in 3D.1 These 3D mapping systems have enabled the display of the cardiac chambers as an anatomical shell upon which voltage, or activation, information can be displayed. Most commonly, colour is used to represent the…
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Author(s):
Caroline H Roney
,
Andrew L Wit
,
Nicholas S Peters
Added:
3 years ago
Determining optimal treatment strategies for complex arrhythmogenesis in AF is confounded by the lack of consensus on the mechanisms causing AF. Fundamental to defining arrhythmogenic mechanisms of AF are the distinctions and interplay between functional features (determined by the electrophysiology of a cell) and structural features (determined by whether a structural or anatomical feature is…
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Author(s):
Serge Sicouri
,
Charles Antzelevitch
Added:
3 years ago
The link between sudden unexplained death in individuals with mental health problems who are administered antipsychotic drugs has been recognised for over a century.1 A clear relationship has emerged over the past 25 years between antipsychotic drugs, prolongation of the QT interval of the ECG, atypical polymorphic tachycardia known as torsade de pointes (TdP) and sudden cardiac death (SCD). A…
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Author(s):
Konstantinos N Aronis
,
Rheeda L Ali
,
Jialiu A Liang
,
et al
Added:
3 years ago
The pathophysiology of AF is complex and incompletely understood to date.1,2 AF is a progressive disease of the atria involving a multitude of mechanisms related to its initiation, maintenance and progression. Experimental evidence suggest that AF is characterised by alternations in atrial size, shape electrophysiology, autonomic innervation, and cardiomyocyte metabolism, as well as development…
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Author(s):
Antonio Zaza
,
Carlotta Ronchi
,
Gabriella Malfatto
Added:
3 years ago
The incidence of ventricular arrhythmias is often related, within an individual, to the rate of their underlying sinus rhythm (heart rate). The direction of this relationship is generally considered to entail some prognostic significance: whereas ectopic activity suppressed by tachycardia is assumed to be benign, an arrhythmia enhanced by tachycardia is regarded with more concern. Is this…
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Added:
6 years ago
Author(s):
Jonathan W Waks
,
Mark E Josephson
Added:
3 years ago
Atrial fibrillation (AF), the most common sustained arrhythmia, is a leading cause of stroke, and is associated with significant morbidity and mortality worldwide. Despite its frequency, clinical importance, and advances in technology and our knowledge of the molecular, ionic and physiological fundamentals of cardiac electrophysiology, our limited understanding of the mechanisms that initiate and…
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Author(s):
Giulio Conte
,
Ulrich Schotten
,
Angelo Auricchio
Added:
3 years ago
The Risk of Atrial Arrhythmias in Inherited Primary Arrhythmia Syndromes
The inherited primary arrhythmia syndromes (IPAS) are a heterogeneous group of diseases caused by mutations in genes encoding for cardiac ion channels. People affected by one of these inherited diseases have no overt structural cardiac abnormalities but are at higher risk of sudden cardiac death due to the occurrence of life…
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Anisotropic Cardiac Conduction
Author(s):
Irum D Kotadia
,
John Whitaker
,
Caroline H Roney
,
et al
Added:
3 years ago
Article
Author(s):
Irina Suman-Horduna
,
Sonya Babu-Narayan
,
Sabine Ernst
Added:
3 years ago
Catheter ablation has moved from ablation of ‘simple’ substrates like accessory pathways,1 atrioventricular nodal re-entrant tachycardias (AVNRTs)2 and re-entrant or focal tachycardia (of either ventricular or atrial origin)3–5 in recent years to more complex arrhythmias such as atrial or ventricular tachycardia (VT) or fibrillation.6–8 Even patients with complex congenital heart disease that may…
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