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Author(s):
Roberto Keegan
,
Cynthia Yeung
,
Adrian Baranchuk
Added:
3 years ago
Chagas disease is an important public health problem in Latin America. Almost 25% of the population (approximately 65 million individuals) are at risk of infection and another 6 million people are affected.1 However, migration and globalisation have resulted in the increased presence of Chagas disease worldwide, particularly in the US and Europe.
Chagas disease is caused by a parasite, the…
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Author(s):
Charles M Pearman
,
Shi S Poon
,
Laura J Bonnett
,
et al
Added:
3 years ago
The goal of arrhythmia eradication in AF continues to be elusive for cardiac electrophysiologists. Although endocardial radiofrequency (RF) catheter ablation is more effective than pharmacological management at maintaining sinus rhythm,1 it is far from perfect, especially in patients with non-paroxysmal AF.2 In an attempt to address this, attention has turned back to the surgical ablation that…
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Author(s):
Nikki Pluymaekers
,
Astrid Hermans
,
Dominik Linz
,
et al
Added:
3 years ago
Author(s):
Demosthenes G Katritsis
Added:
3 years ago
Reviewing recent literature of advances in arrhythmia therapy, I have found most interesting the emergence of antidotes, both general and specific, for the non-vitamin K antagonist oral anticoagulants (NOACs). NOACs offer a relative 50 % reduction in the risk of intracranial haemorrhage and haemorrhagic stroke compared with warfarin that is also maintained in the elderly. There are no clear…
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Author(s):
Georgios Giannopoulos
,
Spyridon Deftereos
Added:
3 years ago
Dear Sir,
We read with great interest the meta-analysis by Pearman et al.1 on the comparison between epicardial ablation for atrial fibrillation and the hybrid approach. The authors should be commended on the way they handled the data. The imbalance between the two meta-analytic cohorts – in terms of the type of atrial fibrillation and left atrial diameter – may have worked to the detriment of…
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Author(s):
Khang-Li Looi
,
Anthony SL Tang
,
Sharad Agarwal
Added:
3 years ago
Heart failure (HF) is a growing and major health burden in western countries. The prevalence of HF is estimated at 1–2 % in the western world, and the incidence approaches 5–10 per 1,000 persons per year.1Cardiac resynchronisation therapy (CRT) has been shown in multiplestudies to improve HF symptoms, quality of life and improve survivals.2–6The two landmark studies, Comparison of Medical Therapy…
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Author(s):
Ghanshyam Shantha
,
Frank Pelosi
,
Fred Morady
Added:
3 years ago
Prevalence of AF and Obstructive Sleep Apnoea
Nonvalvular AF is the most common sustained arrhythmia, affecting nearly 3 million adult Americans.1–4 By 2050, nearly 12–15 million adults in the US will have AF.1 The global prevalence of obstructive sleep apnoea (OSA) is also increasing. OSA is the most common form of sleep-disordered breathing, affecting 10–15% of the general population (6–9% in…
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Author(s):
Yousif Ahmad
,
Gregory YH Lip
Added:
3 years ago
Atrial fibrillation (AF) leads to a prothrombotic state1 and places patients at risk of thromboembolic disease. The most common and serious complication of thromboembolism is stroke, and AF is held responsible for 25 % of all strokes.2 Strokes in the context of AF are associated with a higher mortality, longer hospital stay and lower levels of independence at discharge.3 These factors combine to…
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Author(s):
Andrew Y Chang
,
Daniel Kaiser
,
Aditya Ullal
,
et al
Added:
3 years ago
Atrial fibrillation (AF) is the most frequently encountered arrhythmia in clinical practice.1,2 The prevalence of AF in the United States ranges from 2.7 to 6.1 million, with 5.6 to 12 million additional cases projected by 2050.1 Medicare spending for new AF diagnoses has reached $15.7 billion per year as extrapolated from a 2004–2006 dataset, primarily driven by its complications (e.g. stroke,…
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Author(s):
Charles M Pearman
,
Dhiraj Gupta
Added:
3 years ago
Dear Sir,
We thank Drs Giannopoulos and Deftereos for showing interest in our work.1 They wonder whether a true difference might exist between hybrid and epicardial ablation alone that may have been masked by our combining the results from retrospective observational studies with those from randomised trials.
A fine balance needs to be struck for this type of analysis. On one hand, adopting…
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